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KMID : 0379119830110010064
Korean Journal of Mycology
1983 Volume.11 No. 1 p.64 ~ p.64
Studies on Constituents of Higher Fungi of Korea (37)




Kang Chang-Yul

Abstract
To find antitumor components in Korean basidiomycetes, the carpophores of Armelliela mellea which were collected at the Gwang-neung area in Gyeong-Gi Province in September, 1981 were used in the present study. Twenty-five grams of the dried carpophores were extracted with distilled water on a water-bath at 90¡­100¡É for eight hours. The hot water extract was concentrated under reduced pressure, mixed with three-fold volumes of ethanol, and allowed to stand at 4¡É overnight. The precipitate was centrifugated, redissolved in distilled water, and lyophilized to yield 4.2g of a polysaccharide fraction. It was examined for antitumor activity against sarcoma 180 implanted in ICR mice. This fraction showed 75.7%, 83.9%, and 92.3% of tumor inhibition ratios at the doses of 10, 20, and 50§·/§¸/day, respectively. The chemical analysis of the fraction showed that it contained a polysaccharide(41.3%) anal a protein. The hydrolysates of the polysaccharide moiety contained fucose(4.5%), xylose(1.1%), mannose(19.4%), galact
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